On a warm summer evening in Fort Collins, a jogger paused at the edge of a quiet field. In the fading light, a small shape moved through the grass. At first glance, it looked like any other wild cottontail rabbit. But as it lifted its head, the silhouette seemed unusual, crowned with branching shapes that caught the eye.
Within hours, photos began circulating online. Words like “tentacles” and “invasion” spread quickly across social media. Concerned residents wondered whether a strange new illness was emerging and whether their pets were at risk.
Wildlife officials soon stepped in with reassurance. The unusual growths were not a mysterious new threat, but a known wildlife condition linked to the Shope papillomavirus. The guidance was clear: observe from a distance and avoid handling the animals. Understanding the science behind these sightings helps replace fear with perspective and highlights how nature sometimes surprises us in unexpected ways.

What Is Shope Papillomavirus?
The condition seen in some wild rabbits is associated with the Shope papillomavirus, a virus first described in the 1930s. It primarily affects certain wild rabbit species, especially cottontails. Infected rabbits may develop keratin-based growths that can resemble horns, antlers, or branching structures.
The virus belongs to the papillomavirus family, a large group of viruses that infect various animal species. In rabbits, the growths typically form around the head, face, or ears. While the appearance can be striking, many cases remain limited to cosmetic changes rather than severe illness.
Researchers have studied this virus for decades, and it is not considered a new or rapidly spreading human health threat. It is part of a broader category of wildlife diseases that occur naturally within certain ecosystems.
Why Do the Growths Look So Unusual?
The growths caused by Shope papillomavirus are made primarily of keratin, the same protein found in hair and nails. When keratin accumulates in abnormal patterns, it can form elongated, horn-like structures.
From a distance, these projections can look dramatic, especially in photographs shared online. In reality, they are comparable to benign skin growths observed in many species. In some rabbits, the growths remain small and do not interfere with daily activities. In others, they may become larger over time.
Wildlife experts emphasize that the “tentacle” description is a visual metaphor rather than a biological one. The structures are not moving appendages. They are static growths formed from tissue.
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Cultural Myths and the Jackalope Legend
Long before modern virology, stories circulated across North America about a mythical creature known as the Jackalope. Described as a rabbit with antelope-like horns, the jackalope became a fixture in Western folklore and roadside attractions.
Some historians and folklorists speculate that sightings of rabbits affected by Shope papillomavirus may have inspired these legends. Early observers unfamiliar with the condition could have interpreted the horn-like growths as something fantastical.
While this connection remains speculative, it illustrates how unusual natural phenomena often shape cultural narratives. What once might have fueled campfire stories is now explained through scientific study.
Are Humans or Pets at Risk?
One of the most common questions raised during recent sightings concerns safety. According to wildlife authorities and veterinary experts, Shope papillomavirus is species-specific. There is no evidence that it infects humans, dogs, or cats.
However, experts still advise against touching affected rabbits. The primary reason is to prevent stress to the animal and to reduce the chance of spreading the virus among rabbit populations. Wildlife diseases can sometimes be transmitted between animals through direct contact or contaminated surfaces.
Local agencies such as Colorado Parks and Wildlife have encouraged residents to observe from a distance and report sightings if necessary. This guidance reflects general wildlife safety principles rather than evidence of a broader public health risk.
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Why “Do Not Touch” Is Important
The warning to avoid contact serves multiple purposes. First, wild animals experience stress when handled by humans. Stress can weaken their immune response and make existing conditions worse.
Second, while Shope papillomavirus is not known to infect humans, touching wildlife carries other risks. Wild rabbits may harbor parasites or additional pathogens unrelated to the visible growths. Avoiding direct contact protects both people and animals.
Finally, well-intentioned attempts to “rescue” or assist wildlife can unintentionally cause harm. Professional wildlife rehabilitators are trained to assess when intervention is necessary. In many cases, leaving the animal undisturbed is the most responsible action.
The Science Behind Papillomaviruses
Papillomaviruses are found across many species, including humans and domestic animals. Each virus tends to be highly adapted to its specific host. The rabbit strain differs from human papillomaviruses in important biological ways.
In rabbits, infection typically occurs through small skin abrasions, often facilitated by insects such as mosquitoes or ticks. Once inside the body, the virus can stimulate excessive cell growth in localized areas.
Over time, the immune system of some rabbits may control or reduce the growths. In other cases, the structures may persist. Severe complications are relatively uncommon but can occur if growths interfere with eating or vision.
Scientific research into Shope papillomavirus has contributed to broader understanding of papillomavirus biology. Early studies helped pave the way for later discoveries about viral oncology and immune response.
When Growths Become a Health Concern
Most growths associated with Shope papillomavirus are benign. However, wildlife biologists note that in rare instances, complications can arise. If growths obstruct the mouth, nose, or eyes, they may affect the rabbit’s ability to feed or navigate.
In domestic rabbits, veterinarians may consider surgical removal if the growths impair quality of life. There is no universal cure, but supportive care can help manage individual cases.
For wild populations, natural selection and immune response typically determine outcomes. Monitoring by wildlife agencies helps track patterns without unnecessary intervention.
Why Sightings Sometimes Increase
Social media can amplify wildlife observations rapidly. When one unusual photo circulates, more people begin scanning their surroundings carefully. This increased awareness can create the impression of a sudden surge.
Environmental factors such as insect populations may also influence transmission rates in certain seasons. Warmer months can lead to more insect activity, which may increase the chance of viral spread among rabbits.
Importantly, experts caution against interpreting scattered sightings as evidence of a large-scale outbreak without comprehensive data. Wildlife conditions often fluctuate naturally over time.

Responsible Wildlife Observation
If you encounter a rabbit with unusual growths, experts recommend the following steps.
Observe from a safe distance without approaching or attempting to touch the animal.
Keep pets away to prevent unnecessary stress or potential exposure to parasites.
Contact local wildlife authorities if the animal appears severely impaired.
These actions support both animal welfare and community safety. In many cases, simply allowing nature to take its course is the most appropriate response.
Balancing Concern With Understanding
Images of rabbits with horn-like projections can understandably spark curiosity and concern. The human mind is wired to notice patterns that seem out of the ordinary. Throughout history, such sightings have inspired folklore, art, and storytelling.
Modern science, however, offers tools to interpret these phenomena accurately. By understanding Shope papillomavirus and its species-specific nature, communities can respond calmly rather than react with fear.
Wildlife health issues remind us that ecosystems are complex. Viruses, hosts, insects, and environmental factors interact in ways that may appear dramatic but are often part of long-standing natural cycles.
A Reflection on Human Curiosity
From legends of the jackalope to viral social media posts, unusual rabbits have captured the imagination for generations. Our instinct to share striking images reflects a deep curiosity about the natural world.
Yet curiosity works best when paired with knowledge. Scientific inquiry transforms mystery into understanding, allowing us to appreciate nature’s complexity without unnecessary alarm.
The next time a photo of a rabbit with branching growths appears on your screen, consider both the folklore and the facts. Behind the dramatic silhouette lies a well-documented virus, a resilient wild animal, and a reminder that the natural world is full of surprises waiting to be explored thoughtfully.
Sources
Colorado Parks and Wildlife official wildlife health guidance
Centers for Disease Control and Prevention information on papillomaviruses and species specificity
National Wildlife Health Center resources on wildlife diseases
Peer-reviewed research on Shope papillomavirus in veterinary virology journals